SUBSTITUTED HYDANTOINE

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

CHEN, SHAOQING,HUBY, NICHOLAS,KONG, NORMAN,MOLITERNI, JOHN,MORALES, OMAR

申请号：

AT08786933

公开号：

AT551336T

申请日:

2008.08.06

申请国别(地区):

AT

年份:

2012

代理人:

摘要：

This invention relates to compounds of formula I: or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, and R6 are described in this application. These compounds inhibit the enzymes MEK 1 and MEK2, protein kinases that are components of the MAP kinase signal transduction pathway and as such the compounds will have anti-hyperproliferative cellular activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/