John Anthony Moliterni,Nicholas John Silvester Huby,Norman Kong,Omar Jose Morales,Shaoqing Chen
申请号：
BRPI0815180
公开号：
BRPI0815180A2
申请日:
2008.08.06
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
This invention relates to compounds of formula I: or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, and R6 are described in this application. These compounds inhibit the enzymes MEK 1 and MEK2, protein kinases that are components of the MAP kinase signal transduction pathway and as such the compounds will have anti-hyperproliferative cellular activity.
