e and their use as HSD 1 inhibitors A-S)-1-(1H-benzoimidazole-5-carbonyl)-2,3,4,4A,9,9Crystalline forms of hydrochloride salt of (4A-R,9A-hexahydro-1H-indeno[2,1-B]pyridine-6-carbonitril
MARTIN HANS-JUERGEN,ECKHARDT MATTHIAS,SCHUEHLE MARTIN
申请号：
AP2013006902
公开号：
AP2013006902A0
申请日:
2011.11.04
申请国别(地区):
AP
年份:
2013
代理人:
摘要：
The present invention relates to compounds defined by formula I wherein the variables R1, R2, R3, R4, and m are defined as in claim 1, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of 11&bgr；-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity, and dyslipidemia.
