William H. Robinson,Jeremy Sokolove,Qian Wang,Heidi H. Wong,Mark C. Genovese
申请号:
US13972614
公开号:
US20140066469A1
申请日:
2013.08.21
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Compositions and methods are provided for preventing or treating the pre-clinical early-stages of inflammatory diseases, including autoimmune diseases, degenerative inflammatory diseases, metabolic inflammatory diseases, chronic infection associated with inflammation, cancer associated with inflammation, and other inflammatory diseases by administration to an individual of an effective dose of a synergistic combination of active agents comprising or consisting essentially of an aminoquinoline, e.g. hydroxychloroquine, and a statin, e.g. atorvastatin. Each or both of the active agents can be formulated in various ways, including without limitation a solid oral dosage form.