As for this invention, the composition and method in order to use for the detection of the uncommonness formation in the baretsuto esophagus are dealt with. In addition, as for this disclosure, the method of prescribing the composition which is disclosed in this bill to the person is considered. Therefore, in several features, the composition which is disclosed in this bill and the pharmacy composition which includes the shape medicine which is allowed pharmacy is offered. When it is offered in several features, the composition in this bill, the additional part furthermore is included, the part of that the chemotherapeutic agent and the remedy medicine, the polypeptide and the antibody, is chosen from the group which consists of nuclear acid, the small molecule or the combination in various features.本発明は、バレット食道における異形成の検出に使用するための組成物および方法を対象とする。また、本開示は、本明細書に開示された組成物をヒトに投与する方法を考察する。したがって、いくつかの態様において、本明細書に開示された組成物および薬学的に許容される賦形剤を含む薬学的組成物が提供される。いくつかの態様において、組成物とは本明細書において提供される場合、追加部分をさらに含み、様々な態様において、その部分は化学療法剤、治療剤、ポリペプチド、抗体、核酸、小分子またはその組み合わせからなる群から選ばれる。