DAANEN, JEROME,DEGOEY, DAVID A.,FROST, JENNIFER M.,JINKERSON, TAMMIE,LATSHAW, STEVE,SHI, LEI
申请号：
CA2979534
公开号：
CA2979534A1
申请日:
2016.03.14
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein GAr, L1, Z1and Z2are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Nayl.7 and/or Nayl.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions for the treatment of pain.
