THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
MARUGAN, JUAN JOSE,ZHENG, WEI,XIAO, JINGBO,MCKEW, JOHN
申请号：
CA2891340
公开号：
CA2891340A1
申请日:
2013.11.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The subject invention relates to improved tocopheryl quinone derivatives and tocopherol derivatives having improved pharmacokinetics in vivo that can, in some embodiments, be useful in the treatment of Lysosomal Storage Disorders, restoration of normal mitochondrial ATP production, modulation of intracellular calcium ion concentration and other treatments or therapies. The tocopheryl quinone derivatives and tocopherol derivatives have side chains that have terminally halogenated carbon atoms.
