Paul W. Noble,Dianhua Jiang,Ting Xie,Carol Jiurong Liang
申请号:
US15761403
公开号:
US20180264141A1
申请日:
2016.11.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The described invention provides a method for reducing progression of lung fibrosis after a lung injury comprising administering a therapeutic amount of a therapeutic agent, wherein the therapeutic amount is effective: (a) to modulate expression of a T-box transcription factor in a population of cells in lung and (b) to reduce proliferation of the population of cells in lung expressing the T-box transcription factor. According to some embodiments the T-box transcription factor is Tbx4.