ZOU, JIONG,BOOCK, ROBERT J.,DENNIS, ANDREW TRININ,LEE, TED TANG,SURI, JEFF T.,SZE, DAVID,TAPSAK, MARK A.,WANG, SHANGER,ZHANG, HUASHI
申请号:
CA3002099
公开号:
CA3002099A1
申请日:
2016.12.29
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.