Rosario Lizio;Hans-Ulrich Petereit;Christian Meier;Fang Liu;Michael Damm;Abdul W. Basit
发明人:
Fang Liu,Abdul W. Basit,Rosario Lizio,Hans-Ulrich Petereit,Christian Meier,Michael Damm
申请号:
US12598138
公开号:
US09597293B2
申请日:
2007.05.07
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides a solid dosage form including an inner coating located between a core containing a pharmaceutically active ingredient and an outer enteric coating; wherein the inner coating includes a partially neutralized anionic polymeric material, and at least a carboxylic acid having 2 to 16 carbon atoms the salts thereof or mixtures of the acid and its salt; wherein the outer coating includes an anionic polymeric material which is less or not at all neutralized than the material of the inner coating.