Rosario Lizio;Hans-Ulrich Petereit;Christian Meier;Fang LIU;Michael Damm;Abdul W. Basit
发明人:
Fang LIU,Abdul W. Basit,Rosario Lizio,Hans-Ulrich Petereit,Christian Meier,Michael Damm
申请号：
US13603984
公开号：
US20130058986A1
申请日:
2012.09.05
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides a solid dosage form including an inner coating located between a core containing a pharmaceutically active ingredient and an outer enteric coating； wherein the inner coating includes a partially neutralized anionic polymeric material and at least a carboxylic acid having 2 to 16 carbon atoms, the salts thereof, or mixtures of the acid and its salt； wherein the outer coating includes an anionic polymeric material which is less neutralized than the material of the inner coating or not at all neutralized.
