This invention relates to a novel purified compound PM181104, of formula:of molecular weight 1514 and molecular formula C69H66N18O13S5 which is obtained by fermentation of the microorganism belonging to Kocuria species (ZMA B-1/MTCC 5269). The present invention further relates to processes for the production of the compound PM181104, to the microorganism belonging to Kocuria species (ZMA B-1/MTCC 5269), pharmaceutical compositions containing the novel compound PM181104 as an active ingredient and their use in medicines for treatment and prevention of diseases caused by bacterial infections. The invention includes all stereoisomeric forms and all tautomeric forms of the compound PM181104 and pharmaceutically acceptable salts and derivatives such as esters and ethers thereof.本發明與一種新穎精鍊之化合物PM181104有關,其具有以下的結構:該化合物的分子量為1514,而分子式為C69H66N18O13S5;其藉由屬於庫剋菌種的微生物(ZMA B-1/MTCC 5269)之發酵而得。本發明進一步與製造該化合物PM181104的製程有關,也與屬於庫剋菌種的微生物(ZMA B-1/MTCC 5269)有關,也與包含該新穎化合物PM181104之製藥組成物而作為一有效組成、以及其於藥劑中之用途以治療及避免由細菌感染所引起的疾病有關。本發明包含該化合物PM181104所有的立體異構物形式與所有的互變體形式,以及其製藥上可接受之鹽類與例如其本身酯類與醚類的衍生物。
