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STABLE LYOPHILIZED PREPARATION COMPRISING ANTHRACYCLINE COMPOUND
专利权人:
DAINIPPON SUMITOMO PHARMA CO.; LTD.
发明人:
HIROFUJI, HAJIMU,HASHIMOTO, HOTAKA,TANAKA, KAZUNARI
申请号:
EP09845198
公开号:
EP2436386A4
申请日:
2009.05.27
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention provides a lyophilized amrubicin formulation and a process thereof. In the process, the concentration of the aqueous solution before lyophilization is controlled to about 7.5 mg(potency)/mL or more. Thus, the formulation decreases the production of desaccharified compound and is stable to storage for a long period. The formulation is useful as a cancer chemotherapeutic agent.
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