Stabilized and lyophilized formulation of anthracycline compounds

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专利权人:

Hajimu Hirofuji

发明人:

Hajimu Hirofuji,Hotaka Hashimoto,Kazunari Tanaka

申请号：

US13322151

公开号：

US08785406B2

申请日:

2009.05.27

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention provides a lyophilized amrubicin formulation and a process thereof. In the process, the concentration of the aqueous solution before lyophilization is controlled to about 7.5 mg(potency)/mL or more. Thus, the formulation decreases the production of desaccharified compound and is stable to storage for a long period. The formulation is useful as a cancer chemotherapeutic agent.

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中国工程科技知识中心

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http://www.ckcest.cn/home/