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Stabilized and lyophilized formulation of anthracycline compounds
专利权人:
Hajimu Hirofuji
发明人:
Hajimu Hirofuji,Hotaka Hashimoto,Kazunari Tanaka
申请号:
US13322151
公开号:
US08785406B2
申请日:
2009.05.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a lyophilized amrubicin formulation and a process thereof. In the process, the concentration of the aqueous solution before lyophilization is controlled to about 7.5 mg(potency)/mL or more. Thus, the formulation decreases the production of desaccharified compound and is stable to storage for a long period. The formulation is useful as a cancer chemotherapeutic agent.
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中国工程科技知识中心
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