INGÉNIERIE DE LA PRODUCTION D'UN VARIANT CONFORMATIONNEL DE L'OCCIDIOFONGINE QUI PRÉSENTE UNE ACTIVITÉ INHIBITRICE AUGMENTÉE CONTRE LES ESPÈCES FONGIQUES
The Texas A&M University System;Mississippi State University
发明人:
申请号:
EP13858051.9
公开号:
EP2925774B1
申请日:
2013.11.26
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided.