HOWARD L. LEVINE,WILLIAM J. BOLOGNA,DOMINIQUE DE ZIEGLER
申请号：
MYPI 2010004778
公开号：
MY145215A
申请日:
2002.10.28
申请国别(地区):
MY
年份:
2012
代理人:
摘要：
The invention relates to a pharmaceutical composition for relieving pelvic pain or infertility associated with uterine dysrhythmia. The composition includes a locally-administered anti-dysrhythmic treating agent and a bioadhesive extended-release camer. The composition maybe delivered in an extended release formulation that includes a bioadhesive, water-swellable, water-insoluble, cross-linked polycarboxylic acid polymer, such as polycarbophil. The treating agent may be a local anesthetic, such as lidocaine. The invention also relates to a method of treating or preventing pelvic pain, or treating or improving infertility, by inserting a mixture of an anti-dysrhythmic treating agent and-a bioadhesive carrier into the vagina of the patient to be treated.
