GERT NIKOLAAS MOLL,CORNELIS JOHANNES LEENHOUTS,OSCAR PAUL KUIPERS,ARNOLD JACOB MATHIEU DRIESSEN
申请号：
PT03733622
公开号：
PT1507798E
申请日:
2003.05.26
申请国别(地区):
PT
年份:
2014
代理人:
摘要：
The invention includes a method for harvesting a polypeptide produced by a host cell, wherein the polypeptide has not undergone intracellular posttranslational modification, such as dehydration of a serine or a threonine, and/or thioether bridge formation. The invention also includes a method for producing thioether-containing peptides and dehydroalanine/dehydrobutyrine-containing.peptides, wherein thioether rings may be formed extracellularly.
