MOLL GERT NIKOLAAS,MOLL Gert Nikolaas,LEENHOUTS CORNELIS JOHANNES,LEENHOUTS Cornelis Johannes,KUIPERS OSCAR PAUL,KUIPERS Oscar Paul,DRIESSEN ARNOLD JACOB MATHIEU,DRIESSEN Arnold Jacob Mathieu
申请号:
SI200332339
公开号:
SI1507798T1
申请日:
2003.05.26
申请国别(地区):
SI
年份:
2014
代理人:
摘要:
The invention includes a method for harvesting a polypeptide produced by a host cell, wherein the polypeptide has not undergone intracellular posttranslational modification, such as dehydration of a serine or a threonine, and/or thioether bridge formation. The invention also includes a method for producing thioether-containing peptides and dehydroalanine/dehydrobutyrine-containing.peptides, wherein thioether rings may be formed extracellularly.