PROBLEM TO BE SOLVED: To provide an ophthalmic composition which is excellent in a liquid layer stabilizing effect and a meibum secretion promoting effect and which is useful as a preventive or therapeutic agent for dry eye. SOLUTION: One or more kinds selected from (A) an adrenergic α1 receptor agonist and (B) one or more kinds selected from hyaluronic acid and a salt thereof, panthenol, pantothenic acid and pantothenate, and vitamin A. An ophthalmic composition containing. [Selection diagram] Figure 1【課題】液層安定化効果、マイバム分泌促進効果に優れ、ドライアイ予防剤又は治療剤として有用な眼科用組成物を提供する。【解決手段】（Ａ）アドレナリンα１受容体作動薬から選ばれる１種以上と、（Ｂ）ヒアルロン及びその塩、パンテノール、パントテン酸及びパントテン酸塩、ならびにビタミンＡから選ばれる１種以上とを含有する眼科用組成物。【選択図】図１
