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Granulate containing cannabinoid, method for its manufacture and oral dosage unit comprising such granulate
专利权人:
Echo Pharmaceuticals B.V.
发明人:
De Vries, Jan Albert,Fernandez Cid, Maria Vanesa,Heredia Lopez, Ana Maria
申请号:
AU2013260246
公开号:
AU2013260246A2
申请日:
2013.05.03
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to a granulate comprising granules made up of 40-99 wt.% of lactose particles and 1-60 wt.% of a binding component that holds together the lactose particles within the granules. Said granules have a mass weighted average diameter of 50-500 μm and said binding component is a solid dispersion or a solid solution of 10-75 wt.% of a cannabinoid in 25-80 wt.% of a lipophilic matrix. The lipophilic matrix contains at least 80 wt.% sucrose fatty acid mono-ester, the fatty acid residue being selected from C
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