DE VRIES, JAN ALBERT,FERNANDEZ CID, MARIA VANESA,HEREDIA LOPEZ, ANA MARIA
申请号：
CA2872689
公开号：
CA2872689A1
申请日:
2013.05.03
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to a granulate comprising granules made up of 40-99 wt.% of lactose particles and 1-60 wt.% of a binding component that holds together the lactose particles within the granules. Said granules have a mass weighted average diameter of 50-500 µm and said binding component is a solid dispersion or a solid solution of 10-75 wt.% of a cannabinoid in 25-80 wt.% of a lipophilic matrix. The lipophilic matrix contains at least 80 wt.% sucrose fatty acid mono-ester, the fatty acid residue being selected from C8-C18 fatty acids. The aforementioned granulate can be processed into oral dosage units in the form of tablets for oral delivery. The invention further provides a method for the manufacture of the granulate.
