ACHMATOWICZ, MICHAL,ROMANINI, DANTE,FALSEY, JAMES R.,HERBERICH, BRADLEY J.,THIEL, OLIVER R.
申请号：
CA3071852
公开号：
CA3071852A1
申请日:
2018.08.03
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure relates to a method of capping, reducing, and oxidizingcys-mAbs in order to providehomogenous material for subsequent conjugation reactions. The present methoddemonstrates robust ways to manufacture conjugates ofcysteine-engineered antibodies that offer high yield and consistent productquality.
