ACHMATOWICZ, Michal,ROMANINI, Dante,FALSEY, James R.,HERBERICH, Bradley J.,THIEL, Oliver R.
申请号：
AU2018309090
公开号：
AU2018309090A1
申请日:
2018.08.03
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
The present disclosure relates to a method of capping, reducing, and oxidizing cys-mAbs in order to provide homogenous material for subsequent conjugation reactions. The present method demonstrates robust ways to manufacture conjugates of cysteine-engineered antibodies that offer high yield and consistent product quality.
