Cosmetic use of a composition comprising association of at least one monosaccharide comprising mannose and/or rhamnose and at least one peeling agent, in a medium, to reduce and/or prevent signs of skin aging or its appendages, is claimed. Independent claims are included for: (1) a cosmetic composition comprising a combination of at least one monosaccharide comprising mannose, and/or rhamnose, and at least one peeling agent, in a medium, where the composition does not include the combination of xylitol and mannitol; and (2) a device comprising at least a combination of the monosaccharide comprising mannose and/or rhamnose and at least one peeling agent, where the device is adapted for intraepidermal, intradermal and/or subcutaneous injection. ACTIVITY : Dermatological. MECHANISM OF ACTION : Procollagen of type I synthesis stimulator.La présente invention concerne une composition, notamment cosmétique et/ou dermatologique, comprenant dans un milieu physiologiquement acceptable, l'association d'au moins un monosaccharide choisi parmi le mannose, le rhamnose et leur mélange, et d'au moins un agent desquamant. La présente invention concerne également l'utilisation d'une telle composition, ainsi qu'un dispositif la contenant.