The present invention provides an endoscope apparatus that includes a laser light source for generating excitation light, an endoscopy scope having an irradiation section for irradiating excitation light at an end portion thereof, a CCD incorporating an intensifier for detecting fluorescence generated by excitation light in a tissue, a fluorescence-image generating unit for generating a fluorescence image signal based on a fluorescence signal from the CCD incorporating an intensifier, a distance-measuring unit for generating a distance signal corresponding to the distance between the irradiation section and the tissue, and an amount-of-fluorescence calculating unit for correcting the fluorescence signal with the distance signal to calculate an amount of fluorescence not affected by changes in the distance.