ЦЗЯН Гуан Л. (US),БЕРК Роберт М. (US),ИМ Вха Бин (US),БЕДДИНГФИЛД Фредерик К. (US),УИЛЕР Ларри А. (US),ВИТКАП Скотт М. (US)
申请号：
RU2013108394/15
公开号：
RU2013108394A
申请日:
2011.07.29
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A method for treating skin defects, comprising administering a composition comprising a therapeutically effective amount of a compound having the structure: wherein each dotted line represents the presence or absence of a double bond； R, R, R and R are each independently selected from H and C-C-linear alkyl； R is halogen, C 1-6 alkyl or C 1-6 alkenyl； R is H, C 1-6 alkyl, C 1-6 alkenyl, their salt or amine； n is 0-7； and X is S or O, wherein said administration treats said spots on the skin. 2. The method according to claim 1, characterized in that R is H, R is H, and X is S.3. The method according to claim 1, characterized in that R and R are CH.4. The method according to claim 1, characterized in that R is Cl.5. The method according to claim 1, characterized in that the compound is: .6. The method according to claim 1, characterized in that the skin defect is a superficial wound, scar or wrinkle. The method according to claim 1, characterized in that the composition is administered subcuticularly, subdermally or transdermally, intradermally or subcutaneously. The method according to claim 6, characterized in that the introduction reduces the formation of scars selected from the group consisting of hypertrophic scar, recessed scar, stretch marks and their combinations. The method according to claim 6, characterized in that the skin defect is a wrinkle. The method according to claim 1, characterized in that the composition is administered in an area selected from the group consisting of a face, neck, arms, trunk, back, legs, and combinations thereof. The method according to claim 1, characterized in that the composition is administered at a time selected from the group consisting of "before the surgical incision", during surgery, postoperatively, and combinations thereof. The method according to claim 1, characterized in that said introduction minimizes scarring. The method according to claim 1, from�1. Способ лечения дефектов кожи, включающий введение композиции
