BUTLER, Thomas,CHO, Aesop,KIM, Choung, U.,SAUNDERS, Oliver, L.,ZHANG, Lijun,Parrish, Jay
申请号:
DK15155479
公开号:
DK2937350T3
申请日:
2009.04.22
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
Provided are pyrrolo[1,2-f][1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 1' position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.