GENERAL, SASCHA,TEREBESI, ILDIKO,BRACHT, STEFAN,FUNKE, ADRIAN
申请号：
NZ59094609
公开号：
NZ590946A
申请日:
2009.08.07
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
a) Disclosed herein is a unit dosage form comprising a thin water-soulble film matrix, wherein a) said film matrix comprises at least one water-soluble matrix polymer b) said film matrix comprises particles where said particles comprises at least one progestin and at least one protective agent, and where said particles have a d90 particle size of ?280µm c) said film matrix has a thickness of ?300µm wherein said progestin is selected from the group consisting of levo-norgestrel, norgestrel, norethindrone (norethisterone), dienogest, norethindrone (norethisterone) acetate, ethynodiol diacetate, dydrogesterone, medroxyprogesterone acetate, norethynodrel, allylestrenol, Iynestrenol, quingestanol acetate, medrogestone, norgestrienone, dimethisterone, ethisterone, chlormadinone acetate, megestrol, promegestone, desogestrel, 3-ketodesogestrel, norgestimate, gestodene, tibolone, cyproterone acetate, dienogest and drospirenone, wherein said water-soluble matrix polymer is selected from the group consisting of a cellulosic material, a gum, a protein, a starch, a synthetic polymer, a glucan, and mixtures thereof, and wherein said protective agent is a wax.
