PROCESS TO PREPARE 2- {4- [2 - ({[2- (4-CHLOROPHENYL) -1,3-THIAZOL-4-IL] METHYL} SULFANIL) -3,5-DICIAN-6 MONOCHLORIDRATE - (PIRROLIDIN-1-IL) PIRIDIN-4-IL] PHENOXY} ETHYL-L-ALANYL.

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专利权人:

BAYER PHARMA AKTIENGESELLSCHAFT

发明人:

BIRGIT KEIL,BRITTA OLENIK,DANIEL MEIBOM,FRANZ-JOSEF MAIS,GUIDO BECKER,THOMAS KUHLMANN,WERNER HEILMANN

申请号：

BR112017023852

公开号：

BR112017023852A2

申请日:

2016.05.02

申请国别(地区):

BR

年份:

2018

代理人:

摘要：

to novel precursors for its preparation, and to the preparation and use of crystal modification I of 2-{4-[2-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}sulphanyl)-3,5-dicyano-6-(pyrrolidin-1-yl)pyridin-4-yl]phenoxy}-ethyl-L-alanyl L-alaninate monohydrochloride of the formula (I).

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中国工程科技知识中心

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