The present invention is related to a 3D ventilation device for separating body skin from clothes including an elastic meshed fabric, an elastic framework and a fixing device, wherein the 3D elastic framework which supports and holds the elastic meshed fabric, is fixed by the fixing device to locate between the skin and the clothes, so as to form a ventilative chamber for achieving the separation. Here, the elastic framework can be bent to adapt to different body shapes or portions and adjusted to provide most comfortable wearing angle, so that a proper air flowing can be achieved between the skin or the body portion and the clothes, thereby keeping the skin dry.
