A method for diagnosis of HIT (Heparin-induced thrombocytopenia) in a patient's serum or plasma sample and a system comprising kits for performing the method. The systems include reagents, in the form of diagnostic kits designed for specific platelet analyses; the systems may further include dedicated, simple and easy to use instruments, such as cytometers, suitable for performing said analyses The analytical system is primarily intended for the testing of platelets or autoantibodies or aHa-antibodies reacting with platelets, in specific and important clinical conditions associated with platelet dysfunction and bleeding tendency, and hypercoagulability leading to thrombosis. In addition, testing of platelet functional capacity includes responsiveness to stimulants and inhibitors, and platelet activation markers as indicator of ongoing, in vivo prothrombotic activity.Méthode de diagnostic de la thrombocytopénie sous héparine dans un échantillon de sérum ou de plasma d'un patient, et système comprenant des kits pour la mise en oeuvre de ladite méthode.