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PHARMACEUTICAL COMPOSITION
专利权人:
MedinCell;Anthony RECH;Christophe ROBERGE;Jean-Manuel CROS
发明人:
Christophe ROBERGE,Anthony RECH,Jean-Manuel CROS,Myriam ABBASSI,Adolfo LÓPEZ-NORIEGA,Lea PEBREL,Audrey PETIT,Juliette SERINDOUX
申请号:
US16631604
公开号:
US20200171157A1
申请日:
2018.07.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a biodegradable drug delivery composition comprising a mixture of at least two block copolymers taken among triblock and diblock copolymers comprising: (a) a biodegradable triblock copolymer having the formula: Av-Bw-Ax wherein A is a polyester and B is polyethylene glycol and v and x are from 1 to 3,000 and w is from 3 to 300 and v=x or v≠;x; (b) a biodegradable diblock copolymer having the formula: Cy-Az wherein A is a polyester and C is an end-capped polyethylene glycol and y and z are the number of repeat units with y=2 to 250 and z=1 to 3,000; wherein the weight ratio between (a) and (b) is 1:19 to 5:1; and for at least one of the copolymers according to (a) or (b) A is poly(ε-caprolactone-co-lactide); and (c) at least one pharmaceutically active ingredient.
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中国工程科技知识中心
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