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heterogeneous chain aliphatic poly-n-oxide copolymers and vaccination agents and drugs based on such copolymers
专利权人:
OBCHTCHESTVO S OGRANITCHENNOI OTVETSTVENNOSTYOU "NPO PETROVAKS FARM"
发明人:
ARKADY VASILIEVICH NEKRASOV,NATALYA GRIGORYEVNA PUCHKOVA
申请号:
BR112012032188
公开号:
BR112012032188A2
申请日:
2011.06.20
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The invention relates to the field of synthesizing high molecular weight chemical compounds that exhibit biological activity for the production of highly effective pharmacological preparations and vaccines and, more specifically, to heterochain aliphatic poly-N-oxide copolymers of general formula. (1), where R = N, CH; x = 2 or 4; y = 0 or 2; n = 10 - 1000; q = (0.1 - 0.9)n; z = (0.1 - 0.9)n, which exhibit pharmacological activity, including an antioxidant effect and a therapeutic effect as a detoxicant and immunomodulating agent. Also claimed are: a vaccinating agent comprising an antigen and a formula (1) copolymer as an immunomodulating agent; and a vaccine against hepatitis A and hepatitis B, which contains a vaccine preparation comprising HVA Ag and HBsAg simultaneously or vaccine preparations against hepatitis A and against hepatitis B and a formula (1) heterochain aliphatic poly-N-oxide copolymer, A drug is described which comprises a medicinal substance and a formula (1) copolymer as a carrier. The invention represents a new class of compounds that exhibit a wide range of pharmacological activity and a vaccination effect as well as increased safety in use, and is directed towards increasing manufacturability, cost efficiency and environmental safety in the production of drugs.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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