COMBRETASTATIN A-4-PHOSPHATE PRODRUG SALTS WITH NITROGEN-CONTAINING COMPOUNDS

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专利权人:

BRISTOL-MYERS SQUIBB CO.; PRINCETON

发明人:

VENIT, JOHN J.,DALI, MANDAR V.,DALI, MANISHA M.,HUANG, YANDE,DAHLHEIM, CHARLES E.,TEJWANI, RAVINDRA W.

申请号：

HU0204423

公开号：

HU229055B1

申请日:

2001.09.12

申请国别(地区):

HU

年份:

2013

代理人:

摘要：

Provided herein are novel and useful combretastatin A-4 prodrug salts that increase the solubility of combretastatin A-4, readily regenerate combretastatin A-4 in vivo under normal physiological conditions, and which produce physiologically tolerable products as a result of the regeneration of combretastatin A-4.

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中国工程科技知识中心

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