Isoquinoline derivatives and uses thereof

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专利权人:

パーデュー、ファーマ、リミテッド、パートナーシップ

发明人:

タフェッセ，レイキー,パーク，ジャエ，ヒュン

申请号：

JP2016551246

公开号：

JP6556154B2

申请日:

2015.02.12

申请国别(地区):

JP

年份:

2019

代理人:

摘要：

The Invention provides compounds of Formula (I) and pharmaceutically acceptable salts, solvates, hydrates, N-oxides, or diastereomers thereof: wherein W1, W2, W3, J1, J2, A, R1, R2, R3, R4, R5, a, and b are defined as set forth in the specification. The Invention also provides uses of the compounds of any one of Formulae (I)- (VIII) and the pharmaceutically acceptable salts, solvates, hydrates, N-oxides, or diastereomers thereof. Compounds of the Invention are useful for treating a disorder responsive to blockade of one or more sodium channels. In certain embodiments, Compounds of the Invention are useful for treating pain.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/