The present disclosure relates generally to derivatives of pyrrolobenzodiazepines and antibody-drug conjugates thereof and to methods of using these conjugates as therapeutics and/or diagnostics.本揭露大體上關於吡咯并苯并二氮呯類衍生物及其抗體-藥物共軛物及關於使用這些共軛物作為治療劑和/或診斷劑之方法。