PROBLEM TO BE SOLVED: To provide an external preparation for the skin, which promotes collagen production, prevents and improves age-related changes in the skin such as wrinkles or sagging resulting from decrease in tension or elasticity caused by decrease in collagen and is also effective for healing inflammation or wounds.SOLUTION: The collagen production promoter comprises 0.00001-2.0 wt.% &beta-thujaplicin as an active ingredient and, optionally, further comprises various components generally used in cosmetics, quasi drugs, medicines, etc.COPYRIGHT: (C)2010,JPO&INPIT【課題】コラーゲン産生を促進し、コラーゲンの減少にともなう、はり・弾力の低下、ひいては、しわやたるみといった肌の加齢変化を予防・改善し、加えて炎症や創傷の治癒過程にも有効な皮膚外用剤を提供することを目的とする。【解決手段】有効成分として、0.00001重量%~2.0重量%のβ-ツヤプリシンを含有させ、必要に応じて化粧料、医薬部外品、医薬品等に一般に用いられる各種成分を配合してなるコラーゲン産生促進剤。【選択図】 図2