PROBLEM TO BE SOLVED: To provide a collagen gel-shrinking agent that shrinks collagen gel comprising collagen and a fibroblast, and an AGE production inhibitor and/or a saccharification inhibitor.SOLUTION: The collagen gel-shrinking agent uses silybin maltoside represented by the following formula (1), in which the fact that a function of shrinking collagen in particular is remarkably improved even under high concentration glucose conditions compared with the other silybin compounds, has been recognized.【課題】コラーゲンおよび線維芽細胞を含むコラーゲンゲルを収縮させるコラーゲンゲル収縮剤、ＡＧＥ生成抑制剤及び又は糖化抑制剤の提供。【解決手段】高濃度グルコース状況下においても、他のシリビン化合物と比較して特にコラーゲンを収縮する機能が顕著に向上することが認められた下記式（１）のシリビンマルトシドであるコラーゲンゲル収縮剤。【選択図】なし
