A method of modeling a structure of a coronary artery of a subject may include: forming a learning-based shape model of the structure of the artery, based on positions of landmarks acquired from three-dimensional images receiving a target image and/or modeling the artery structure included in the target image, using the model. An apparatus for modeling a structure of a coronary artery may include: a memory configured to store a learning-based shape model of the artery, the learning-based shape model being formed based on positions of a plurality of landmarks acquired from three-dimensional images, the plurality of the landmarks corresponding to the artery a communication circuit configured to receive a target image and/or a processing circuit configured to model the artery structure included in the target image, using the model.