ANTIBODY OR FRAGMENT THEREOF THAT BINDS TO PDGFR-ALPHA, NUCLEIC ACID ENCODING THE SAME, VECTORS, HOST CELLS AND CONJUGATES COMPRISING SUCH ANTIBODY AND USES OF SUCH ANTIBODY IN THE MANUFACTURE OF MEDICAMENTS
BLAKEY, DAVID, CHARLES;LAING, NAOMI;CARTLIDGE, SUSAN ANN;YANG, XIADONG;KANG, JASPAL, SINGH;TAYLOR, LAURA;GAZIT-BORNSTEIN GADI;FOLTZ, IAN;ASTRAZENECA AB
发明人:
申请号：
IL22283312
公开号：
IL222833D0
申请日:
2012.11.01
申请国别(地区):
IL
年份:
2012
代理人:
摘要：
Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha.
