Laing, Naomi,Kang, Jaspal Singh,Foltz, Ian,Gazit-Bornstein, Gadi,Yang, Xiao-Dang,Cartlidge, Susan Ann,Blakey, David Charles,Taylor, Laura
申请号:
AU2012202865
公开号:
AU2012202865A1
申请日:
2012.05.16
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2012202865A120120607.pdf#####C \NRPoIlDC KXG4129971_ DOC-15/15/20112 ABSTRACT Targeted binding agents directed to the antigen I)GFR-alpha and uses of such agents are disclosed herein. More spccilically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of lDGFR-alpha.1/4 LO M ~CO Nll C)~Zj-C) 0 +0 04>. < 0 + ~I ( o 0 (0 (N 0 (N 0 - 0- 0 0 00 0 ) C) co (D ,I-C0C