Disclosed is a system and method for configuring a personalized neuro-stimulation module, comprising measuring the electro-physiology signal of ab individual and establishing a personalized neuro-stimulation module having preset modulated parameters, wherein the personalized neuro-stimulation module generates human physiology parameters according to the modulated parameters, and further analyzing and modulating the physiology parameters according to a parameter prioritized algorithm, thereby enabling the output physiology parameter of the personalized neuro-stimulation module to match with the measured electro-physiology signal and thus realizing the objective of simulating human neuro-stimulation.一種建構個人化神經刺激模型之系統及方法，首先，量測個人之電生理訊號，且建立具有預設之模型參數的個人化神經刺激模型，其中，該個人化神經刺激模型依據該模型參數產生人體生理參數，接著，分析該模型所產生之人體生理參數並根據參數優化演算法調整該模型之模型參數，俾使該個人化神經刺激模型所輸出之人體生理參數匹配於所量測之該電生理訊號。據此，本發明可實現生物醫學上模擬神經刺激反應之個人化神經刺激模型。
