This invention relates to novel oxazolidinone derivatives having potential antimicrobial activity over wide spectrum of pathogens and modulation of coagulation properties of blood-clotting cascade. More particularly, the invention relates to silicon analogs of oxazolidinone compounds, to pharmaceutical compositions and to the synthesis of the oxazolidinone derivatives. The invention further relates to methods of treating a subject suffering with gram positive pathogens including those resistant to methicillin and vancomycin using the compound(s) or modulation of coagulation properties of blood-clotting cascade or compositions of the oxazolidinone