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USE OF WATER-SOLUBLE POLYMERS BASED ON N-VINYLPYRROLIDONE AND ACRYLIC ACID AS PHARMACEUTICAL ADJUVANTS
专利权人:
BASF SE
发明人:
Heiko Alexander Schiffter,Maximilian Angel,Karl Kolter,Felicitas Guth
申请号:
US15751889
公开号:
US20180228730A1
申请日:
2016.08.17
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Use of a water-soluble polymer having a solubility in water of greater than 5% (m/m) in the pH range of 1 to 13 and which is obtained by free-radically initiated polymerization of a monomer mixture of i) 70 to 90% by weight N-vinylpyrrolidone and ii) 10 to 30% by weight acrylic acid, wherein the sum total of i) and ii) corresponds to 100% by weight, for the formulation of basic active ingredients sparingly soluble in water, wherein the active ingredients in uncharged form or as hydrochloride have a solubility of less than 0.1% (m/m) in water, artificial intestinal juice or gastric juice.
来源网站:
中国工程科技知识中心
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