Heiko Alexander Schiffter,Maximilian Angel,Karl Kolter,Felicitas Guth
申请号：
US15753186
公开号：
US20180235885A1
申请日:
2016.08.17
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Water-soluble polymeric salts of medicaments sparingly soluble in water consisting of a cationogenic medicament which, in uncharged form or as hydrochloride, has a solubility of less than 0.1% (m/m) in water, artificial intestinal juice or gastric juice, and an anionogenic water-soluble polymer having a solubility in water of at least 5% (m/m) in the pH range of 1 to 13 and which is obtained by free-radically initiated polymerization of a monomer mixture of i) 70 to 90% by weight N-vinylpyrrolidone and ii) 10 to 30% by weight acrylic acid, wherein the sum total of i) and ii) corresponds to 100% by weight.
