an IL-6 receptor is expressed in cells of human pancreatic cancer cell lines and IL-6 enhances the chemotactic and migratory activities and . intracellular signaling of pancreatic cancer cells and thus pancreatic cancer can be treated by inhibiting IL-6. Furthermore, the present inventors found that neural invasion of human pancreatic cancer can be suppressed, from the results of administering IL-6 inhibitors to neural invasion model mice.
