PROBLEM TO BE SOLVED: To provide a novel pancreatic cancer treating agent.SOLUTION: The invention provides a composition for the treatment of pancreatic cancer containing an antimetabolite, or an IL-6 inhibitor which is administered in combination with the antimetabolite. Preferably, the IL-6 inhibitor is a substance binding to IL-6 receptors, such as an anti-IL-6 receptor antibody, and the antimetabolite is a cytosine analog, such as a gemcitabine.EFFECT: Reduction in size of the metastatic focus from human pancreatic carcinoma and elimination of ascites are possible.SELECTED DRAWING: None【課題】新規な膵癌治療剤の提供。【解決手段】代謝拮抗剤を含有する、または、代謝拮抗剤と併用して投与する、IL-6阻害剤を含む膵癌治療用組成物。IL-6阻害剤が抗IL-6受容体抗体などのIL-6受容体に結合する物質であり、代謝拮抗剤がゲムシタビンなどのシトシン類縁体であることが好ましい。【効果】ヒト膵癌からの転移巣の縮小および腹水の消失が可能。【選択図】なし
