Methods and compositions for gene inactivation

• 收藏
• 分享

专利权人:

发明人:

Dale Ando,Michael C. Holmes,Gary Ka Leong Lee

申请号：

US14054042

公开号：

US09434776B2

申请日:

2013.10.15

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Disclosed herein are methods and compositions for inactivating CCR-5 genes, using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding ZFNs, vectors comprising polynucleotides encoding ZFNs, such as adenovirus (Ad) vectors, and cells comprising polynucleotides encoding ZFNs and/or cells comprising ZFNs are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/