KIM, HYUNG SEOKR,김형서,CHO, JUNG HYUNKR,조정현,KIM, JIN CHEULKR,김진철,KIM, YOUG ILKR,김용일,PARK, JAE HYUNKR,박재현,WOO, JONG SOOKR,우종수
申请号:
KR1020150093777
公开号:
KR1020160002411A
申请日:
2015.06.30
申请国别(地区):
KR
年份:
2016
代理人:
摘要:
Provided is a composite formulation comprising a core which contains a first active agent and a film coating layer which contains a 5-&alpha-reductase inhibitor. The film coating layer is prepared by coating the composite formulation with a film coating solution comprising a film coating agent dissolved in a mixed solvent of 30 to 80 wt% of an organic solvent and water. Accordingly, the composite formulation of the present invention has a high release rate of active ingredients and homogeneity of content, while maintaining stabilized properties of the coating layer against common impacts from the outside.COPYRIGHT KIPO 2016본 발명은 제 1 활성성분을 함유하는 코어 및 5-α-환원효소 억제제를 함유하는 필름코팅층을 포함하는 복합제제로서,상기 필름코팅층은 유기용매의 비율이 30~80 중량%인 물과 유기용매의 혼합용매 중에 필름코팅 기제가 용해된 필름코팅액으로 코팅된 것인 복합제제 및 그 제조방법을 제공한다.