A patient positioning device is provided with a patient support, a movement device, and a pivoting device connecting the patient support to the movement device. The movement device moves the patient support by enabling translational movements of the patient support in directions of the three spatial axes x, y, z of a coordinate system and rotational movements of the patient support about the three spatial axes x, y, z. The pivoting device enables a pivot movement of the patient support relative to the movement device about a horizontal pivot axis. The movement device is preferably a robot arm.